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KMID : 0545119970070060397
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Journal of Microbiology and Biotechnology
1997 Volume.7 No. 6 p.397 ~ p.401
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Characterization of Streptomyces sp. AMLK-135 Producing Anti-MRSA Antibiotics
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Lee, Min Jeong
Lim, Dae Seog/Lee, Myung Sub/Yoon, Won Ho/Kim, Chang Han
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Abstract
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The present research program was conducted to charactcrize a strain of actinomycetes producing an anti methicillin-resistant Staphylococcus aureus, (MRSA) antibiotic Soil samples were collected from various sites in Korea and a number of aetinomycetes were isolated from the soil samples by applying selective agar for actinomycetes. Among over 400 isolates, a strain (AMLK-135) producing anti-MRSA antibiotic against S. aureus TK 784 was selected According to the morphological and physiological characteristics, the strain AMLK-135 was confirmed to contirmed to belong to the genus Streptomyces. From the results of species identification with the TAXON program the strain AMLK-135 was shown to belong to major cluster 5 (Streptomyces exfoliatus), but it had a low simple matching coefficient (S_sm) value to member organisms of major cluster 5 Percentage (%) of strain further away of the strain AMLK-135 was low (1.9400) and it was placed further away than the outer-most members in major cluster 5. Therefore, the strain AMLK-135 was low (1.9400) and it was placed further away than the outer-most memners in major cluster 5. Therefore the stain AMLK-135 was identified as new species of the genus Streptomyces.
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KEYWORD
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